Bilateral Wilms’ tumour: An international comparison of treatments and outcomes

Abstract Introduction: Wilms' tumour is the most common childhood renal malignancy, with 5–10% of cases presenting bilaterally 1. However, there currently no consensus between centres on optimal management bilateral tumours. This an international multi-centre case series comparing and outcomes tumours low-income (LIC) high-income (HIC). Methods: Patients were identified from four tertiary referral internationally. Data collected baseline characteristics, disease status, treatment used clinical outcomes. Results compared individual as well groups Results: for forty patients. Most patients received preoperative chemotherapy (n = 38, 95%). The surgical procedures nephron-sparing surgery 10, 25%) nephrectomy partial 20, 50%). Ten-year survival after was follows: LIC's n 13 (65%); HIC's 20 (100%) (p 0.01). Discussion: significantly higher in HIC's. Our results show this may be caused by patient factors such later presentation more advanced centres. comparative first to report a large number multiple centres, compare key